Ramona Quimby is a grade-school student with a big imagination. She often clashes with her no-nonsense teacher Mrs. Meacham. When Ramona's upbeat dad Robert loses his job, the family - including her teenage sister, Beezus, and their practical-minded mother - must make major adjustments, like dad learning how to run the house. Ramona dreams up various plans to make money so that she can save their house.